Spreading Awareness: Educating Ourselves and Each Other

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I am a member of several Osteonecrosis (Avascular Necrosis), Factor V Leiden, MTHFR and Blood clotting support groups on yahoo and Facebook. I often write about my blog and post it in the different groups and hope that I can … Continue reading

The importance of being tested for mutations in the MTHFR gene

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When there is a mutation in the MTHFR gene in an individual, along with another thrombophilic factor (ie. Factor V Leiden), the risk for thrombophilia is greatly increased. MTHFR stands for Methylenetetrahydrofolate reductase. Another term for MTHFR is NAD(P)H 5,10-methylenetetrahydrofolate. … Continue reading

Why ON (AVN) sufferers should have their homocysteine levels checked

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Homocysteine is an amino acid produced by the body. Elevated homocysteine levels are linked to high concentrations of endothelial asymmetric dimethylarginine (ADMA); a chemical found in blood plasma.  ADMA interferes with the synthesization of Nitric Oxide from L-Arginine. Nitric Oxide is … Continue reading

Why being tested for the e(NOS) mutation is important

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Yesterday I posted this under clotting disorders: What is the eNOS (Endothelial Nitric Oxide Synthase) gene T786C mutation When someone has a mutation in their eNOS gene it means that their body doesn’t produce an amino acid called L-Arginine (also … Continue reading

Grieving for the Life you Lost

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A year ago, yesterday, my husband and I moved to San Francisco from New York for a fresh start.  We had had a bad two years personally and work wise and we saw our move to the West coast as … Continue reading

Idiopathic Osteonecrosis (Avascular Necrosis)

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A lot of Osteonecrosis (Avascular Necrosis) patients are told their ON (AVN) is idiopathic. Meaning doctors can’t find a reason as to why that person developed ON (AVN). There is a reason for everything, it might not be known at … Continue reading