Causes/Etiology of ON(AVN)

Osteonecrosis also known as Avascular Necrosis (bone infarction, aseptic necrosis, ischemic bone necrosis) is when your bone dies due to a lack of blood supply.

Known causes of ON (AVN):

  • Alcohol Abuse
  • Steroid treatment
  • Chemotherapy
  • Traumatic blunt force injury
  • Blood clotting disorders (ie. Factor V Leiden, MTHFR)

Where ON (AVN) presents itself:  Osteonecrosis (Avascular Necrosis) usually effects the joints, the most common being the hips and the knees. However, the disease can effect any joint in the body (shoulder, ankles etc.). The disease usually presents itself bilaterally, meaning if you have it in your right hip you will most likely also have it in you left hip.

Diagnosis: In the early stages of ON (AVN) it is NOT detectable on an X-Ray. It can be seen on a a bone scan, but the best way of detecting ON (AVN) is by an MRI.

ON (AVN) in children is referred to as Legg-Calvé-Pethes Syndrome (you will find a paper concerning this syndrome under clinical papers).

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One thought on “Causes/Etiology of ON(AVN)

  1. Pingback: Welcome Osteonecrosis/Avascular Necrosis Sufferers | Osteonecrosis (Avascular Necrosis)

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